Fig. 1 · Structure
Documents & Downloads
Dichlorobenzamil hydrochloride
Na+/Ca2+ Exchanger Inhibitor
Dichlorobenzamil hydrochloride is a selective inhibitor of the Na+/Ca2+ exchanger, which plays a crucial role in calcium homeostasis and excitability in neuronal cells. This compound effectively diminishes Na+/Ca2+ exchanger-mediated inward currents in response to activation of metabotropic glutamate receptors, particularly in second-order baroreceptor neurons within the rat nucleus tractus solitarius. Its use in research can advance the understanding of calcium signaling pathways and their implications in cardiovascular and neurological functions.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 928621-15-2 |
| Applications | Na+/Ca2+ Exchanger Inhibitor |
| Formula | C13H13Cl4N7O |
| Molecular Weight | 425.10 |
| Synonyms | 3',4'-Dichlorobenzamil (hydrochloride); L-594881 (hydrochloride) |
| SMILES | O=C(C1=NC(Cl)=C(N)N=C1N)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.