Fig. 1 · Structure
Documents & Downloads
Diclofenac acyl glucuronide
Cat. No.
A70144
CAS
64118-81-6
Endogenous Metabolite
Diclofenac acyl glucuronide (D-1-O-G) is an endogenous metabolite that results from the conjugation of diclofenac. This compound plays a significant role in the pharmacokinetics of non-steroidal anti-inflammatory drugs (NSAIDs) and is implicated in gastrointestinal toxicity, particularly small intestinal ulceration in rat models. It serves as a valuable tool for studying drug metabolism and the effects of NSAIDs on the digestive system in research applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 64118-81-6 |
| Applications | Endogenous Metabolite |
| Formula | C20H19Cl2NO8 |
| Molecular Weight | 472.27 |
| Synonyms | D-1-O-G |
| SMILES | O[C@H]1[C@H](OC(CC2=CC=CC=C2NC3=C(Cl)C=CC=C3Cl)=O)O[C@H](C(O)=O)[C@@H](O)[C@@H]1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.