Dicoumarol-d8 is a deuterated form of Dicoumarol, targeting NAD(P)H:quinone oxidoreductase 1 (NQO1) and pyruvate dehydrogenase kinase 1 (PDK1). It exhibits inhibitory activity with IC50 values of 0.37 μM for NQO1 and 19.42 μM for PDK1. This stable isotope-labeled reagent is valuable in biochemical research and metabolic studies, providing insights into enzyme function and regulation.
Dicoumarol-d8 is a deuterated form of Dicoumarol, targeting NAD(P)H:quinone oxidoreductase 1 (NQO1) and pyruvate dehydrogenase kinase 1 (PDK1). It exhibits inhibitory activity with IC50 values of 0.37 μM for NQO1 and 19.42 μM for PDK1. This stable isotope-labeled reagent is valuable in biochemical research and metabolic studies, providing insights into enzyme function and regulation.
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