Documents & Downloads

Dicycloplatin

DNA Damage Inducer

Dicycloplatin is a DNA damage inducer that primarily activates key regulatory proteins, including biphosphorylated checkpoint kinase 2 (CHK2), breast cancer 1 (BRCA1), and triphosphorylated p53. Its mechanism of action facilitates cell cycle arrest, inhibits proliferation, and promotes apoptosis in various cancer cell lines, specifically prostate cancer PC3 cells and lung cancer NCI/H446 cells. Dicycloplatin is applicable in cancer research, providing insights into therapeutic approaches targeting DNA damage response pathways.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inducer
CAS Number	287402-09-9
Applications	DNA Damage Inducer
Formula	C₁₂H₂₀N₂O₈Pt
Molecular Weight	515.38
SMILES	O=C(C1(CCC1)C(O)=O)O.O=C2[O-][Pt+2]([NH3])([NH3])[O-]C(C23CCC3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.