Fig. 1 · Structure
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Didesmethylpromazine
Trypanothione Reductase Inhibitor
Didesmethylpromazine is a selective inhibitor of trypanothione reductase, demonstrating an IC50 of 1412 μM against Trypanosoma cruzi trypanothione reductase. This compound is valuable for investigating the biochemical pathways associated with trypanosome and leishmania infections. Its inhibitory action provides a potential avenue for studying therapeutic targets in parasitic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2095-21-8 |
| Applications | Trypanothione Reductase Inhibitor |
| Formula | C15H16N2S |
| Molecular Weight | 256.37 |
| SMILES | S1C=2C=CC=CC2N(C=3C=CC=CC13)CCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.