Diethyl 10-bromodecylphosphonate is a phosphonate compound designed for use as a linker in PROTAC (proteolysis-targeting chimeras) synthesis. This alkyl chain-based linker facilitates the recruitment of ubiquitin ligases to target proteins, promoting their degradation via the ubiquitin-proteasome pathway. Its incorporation into PROTACs enables targeted protein degradation, making it valuable in drug discovery and cellular biology research.
Diethyl 10-bromodecylphosphonate is a phosphonate compound designed for use as a linker in PROTAC (proteolysis-targeting chimeras) synthesis. This alkyl chain-based linker facilitates the recruitment of ubiquitin ligases to target proteins, promoting their degradation via the ubiquitin-proteasome pathway. Its incorporation into PROTACs enables targeted protein degradation, making it valuable in drug discovery and cellular biology research.
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