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Diethyl 10-bromodecylphosphonate

PROTAC Linkers

Diethyl 10-bromodecylphosphonate is a phosphonate compound designed for use as a linker in PROTAC (proteolysis-targeting chimeras) synthesis. This alkyl chain-based linker facilitates the recruitment of ubiquitin ligases to target proteins, promoting their degradation via the ubiquitin-proteasome pathway. Its incorporation into PROTACs enables targeted protein degradation, making it valuable in drug discovery and cellular biology research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	272785-01-0
Applications	PROTAC Linkers
Formula	C₁₄H₃₀BrO₃P
Molecular Weight	357.26
SMILES	O=P(OCC)(CCCCCCCCCCBr)OCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.