Fig. 1 · Structure
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Diethylene glycol diacetate
PROTAC Linker
Diethylene glycol diacetate is a polyethylene glycol (PEG)-based linker utilized in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound serves as a crucial component for enhancing the selectivity and efficacy of targeted protein degradation strategies. It plays a significant role in drug discovery and development by facilitating the formation of PROTACs that can selectively target and eliminate specific proteins in various biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 628-68-2 |
| Applications | PROTAC Linker |
| Formula | C8H14O5 |
| Molecular Weight | 190.19 |
| SMILES | CC(OCCOCCOC(C)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.