Fig. 1 · Structure
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Diminazene aceturate
Trypanocidal Agent
Diminazene aceturate is a potent trypanocidal agent primarily targeting Trypanosoma parasites. Its mechanism of action involves binding to trypanosomal kinetoplast DNA (kDNA) non-intercalatively, specifically at sites rich in adenine-thymine base pairs, leading to inhibition of parasite replication. In addition to its trypanocidal properties, Diminazene aceturate also activates angiotensin-converting enzyme 2 (ACE2) and exhibits strong anti-inflammatory activities, making it valuable for various research applications, particularly in veterinary medicine and investigations of inflammatory pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 908-54-3 |
| Applications | Trypanocidal Agent |
| Formula | C22H29N9O6 |
| Molecular Weight | 515.52 |
| Synonyms | Diminazene diaceturate |
| SMILES | O=C(O)CNC(C)=O.N=C(C1=CC=C(/N=N/NC2=CC=C(C(N)=N)C=C2)C=C1)N.O=C(O)CNC(C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.