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Diphenidol HCl

M2/M3 antagonist

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Catalog No. A14244

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Diphenidol HCl 100mg A14244-100
$60.00
Diphenidol HCl 500mg A14244-500
$220.00
Diphenidol HCl 10mM * 1mL in DMSO A14244-10mM-D
$64.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02.

Diphenidol HCl

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Chemical Information

Catalog Num A14244
Actions No
M. Wt 345.91
Formula C21H28ClNO
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 3254-89-5
Synonyms 0
SMILES C1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.Cl

Biological Activity

Description
Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02.
Targets
M2 mAChR M2 mAChR M3 mAChR

Solubility

Solubility (25°C)* In vitro DMSO 69 mg/mL (199.47 mM)
Water 13 mg/mL (37.58 mM)
Ethanol 36 mg/mL heating (104.07 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.91 mL 144.55 mL 289.09mL
0.5 mM 5.78 mL 28.91 mL 57.82 mL
1 mM 2.89 mL 14.45 mL 28.91 mL
5 mM 0.58 mL 2.89 mL 5.78 mL

*The above data is based on the productmolecular weight 345.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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