DL-017 is a Quinazoline derivative that exhibits potent inhibition of α1-adrenergic receptors, with an IC50 of approximately 0.90 nM, and Na+ channels, with an IC50 of 404 nM. Its robust antihypertensive activity makes DL-017 a valuable reagent for studying cardiovascular mechanisms and exploring therapeutic avenues for hypertension. This compound serves as a crucial tool in pharmacological research and drug development focused on adrenergic modulation and ion channel interactions.
DL-017 is a Quinazoline derivative that exhibits potent inhibition of α1-adrenergic receptors, with an IC50 of approximately 0.90 nM, and Na+ channels, with an IC50 of 404 nM. Its robust antihypertensive activity makes DL-017 a valuable reagent for studying cardiovascular mechanisms and exploring therapeutic avenues for hypertension. This compound serves as a crucial tool in pharmacological research and drug development focused on adrenergic modulation and ion channel interactions.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
