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Biological Activity
Guanabenz acetate is an a2A-AR adrenergic agonist and IGRS (imidazoline I2 binding site) selective ligand.
Targets
α2a-adrenergic receptor | α2b-adrenergic receptor | α2c-adrenergic receptor | ||
8.25(pEC50) | 7.01(pEC50) | <5(pEC50) |
In vitro (25°C) | DMSO | 56 mg/mL (192.35 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (17.17 mM) | ||
In vivo | 4% DMSO+30% PEG 300+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 34.35 mL | 171.74 mL | 343.49 mL |
0.5 mM | 6.87 mL | 34.35 mL | 68.7 mL |
1 mM | 3.43 mL | 17.17 mL | 34.35 mL |
5 mM | 0.69 mL | 3.43 mL | 6.87 mL |
*The above data is based on the productmolecular weight 291.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13635 |
---|---|
Actions | Agonist |
CAS No. | 23256-50-0 |
Formula | C10H12Cl2N4O2 |
M. Wt | 291.13 |
Purity | >98% |
SMILES | CC(=O)O.C1=CC(=C(C(=C1)Cl)/C=N/N=C(N)N)Cl |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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