Fig. 1 · Structure

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DL-4-Hydroxy-2-ketoglutarate

Cat. No. A74340 CAS 1187-99-1

Endogenous Metabolite

DL-4-Hydroxy-2-ketoglutarate acts as a substrate for the enzymes glutamic oxalacetic aminotransferase (GOT) and 2-keto-4-hydroxyglutarate aldolase, mediating the reversible conversion of 2-keto-4-hydroxyglutarate to pyruvate and glyoxylate. This endogenous metabolite is valuable in mass spectrometry applications for the rapid analysis of negatively charged, water-soluble cellular metabolites, aiding in metabolic pathway studies and biomarker discovery.

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Specifications

Manufacturer Adooq Bioscience
Actions Substrate
CAS Number 1187-99-1
Applications Endogenous Metabolite
Formula C5H6O6
Molecular Weight 162.10
SMILES
O=C(C(CC(C(O)=O)O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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