DL-Kynurenine is an endogenous metabolite in the tryptophan metabolic pathway that can effectively cross the blood-brain barrier. It demonstrates a bidirectional regulatory effect on neural excitability and can exacerbate the convulsive and lethal effects of strychnine. As a precursor to Kynurenic acid, which antagonizes the glycine site of NMDA receptors, DL-Kynurenine serves as a valuable tool for research into neurotoxicity and excitatory neurotransmitter modulation.
DL-Kynurenine is an endogenous metabolite in the tryptophan metabolic pathway that can effectively cross the blood-brain barrier. It demonstrates a bidirectional regulatory effect on neural excitability and can exacerbate the convulsive and lethal effects of strychnine. As a precursor to Kynurenic acid, which antagonizes the glycine site of NMDA receptors, DL-Kynurenine serves as a valuable tool for research into neurotoxicity and excitatory neurotransmitter modulation.
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