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DL002

Catalog No.: A43260
ADC Linker
DL002 is an antibody-drug conjugate (ADC) linker designed for the synthesis of conjugates featuring BCL-2 family protein degraders. It plays a critical role in tumor research by facilitating targeted delivery of cytotoxic agents, thereby enhancing therapeutic efficacy. This reagent is essential for studies aiming to investigate the modulation of BCL-2 proteins in cancer treatment strategies.
DL002 3049680-91-0 ADC Linker
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDL002 is an antibody-drug conjugate (ADC) linker designed for the synthesis of conjugates featuring BCL-2 family protein degraders. It plays a critical role in tumor research by facilitating targeted delivery of cytotoxic agents, thereby enhancing therapeutic efficacy. This reagent is essential for studies aiming to investigate the modulation of BCL-2 proteins in cancer treatment strategies.
Product Information
Catalog NumA43260
FormulaC109H139ClF3N19O17S5
Molecular Weight2240.16
CAS Number3049680-91-0
SMILESCC(C)(C1)CCC(C2=CC=C(C=C2)Cl)=C1CN3CCN(C4=CC=C(C=C4)C(NS(=O)(C5=CC(S(C(F)(F)F)(=O)=O)=C(C=C5)N[C@@H](CSC6=CC=CC=C6)CCN7CCN(CC7)C(CCCCCC(N[C@@H](C(C)(C)C)C(N8[C@@H](C[C@H](C8)OC(OCC9=CC=C(C=C9)NC([C@H](CCCCN)NC([C@H](C(C)C)NC(CCCCCN%10C=C(C%11=CN=C(S(C)(=O)=O)N=C%11)N=N%10)=O)=O)=O)=O)C(N[C@H](C%12=CC=C(C%13=C(C)N=CS%13)C=C%12)C)=O)=O)=O)=O)=O)=O)CC3
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Antibody-drug Conjugates (ADC) > ADC Linker