DMAC-SPDB-sulfo

Catalog No.: A43272
ADC Linker
DMAC-SPDB-sulfo is a cleavable linker specifically designed for use in the synthesis of antibody-drug conjugates (ADCs). This sulfo-based compound facilitates the controlled release of therapeutic agents upon cellular internalization, allowing for targeted delivery and enhanced efficacy. Researchers can utilize DMAC-SPDB-sulfo in the development of ADCs to improve treatment precision in various cancer therapies, aiding in the advancement of targeted drug delivery systems.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMAC-SPDB-sulfo is a cleavable linker specifically designed for use in the synthesis of antibody-drug conjugates (ADCs). This sulfo-based compound facilitates the controlled release of therapeutic agents upon cellular internalization, allowing for targeted delivery and enhanced efficacy. Researchers can utilize DMAC-SPDB-sulfo in the development of ADCs to improve treatment precision in various cancer therapies, aiding in the advancement of targeted drug delivery systems.
Product Information
Catalog NumA43272
FormulaC16H19N3O8S3
Molecular Weight477.53
CAS Number663599-07-3
SMILESO=C(ON1C(C(S(=O)(O)=O)CC1=O)=O)CCCSSC2=NC=C(C(N(C)C)=O)C=C2
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2