DMAC-SPP

Catalog No.: A43057
ADC Linker
DMAC-SPP is a cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). It facilitates targeted delivery of cytotoxic agents to cancer cells by releasing the drug in response to specific intracellular conditions. This reagent is essential for enhancing the efficacy and selectivity of ADCs in therapeutic applications, contributing to advancements in cancer treatment research.
Grouped product items
Size Stock
5mg
10mg
50mg
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDMAC-SPP is a cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). It facilitates targeted delivery of cytotoxic agents to cancer cells by releasing the drug in response to specific intracellular conditions. This reagent is essential for enhancing the efficacy and selectivity of ADCs in therapeutic applications, contributing to advancements in cancer treatment research.
Product Information
Catalog NumA43057
FormulaC17H21N3O5S2
Molecular Weight411.50
CAS Number663599-10-8
SMILESCC(SSC1=C(C(N(C)C)=O)C=NC=C1)CCC(ON2C(CCC2=O)=O)=O
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