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DNA Gyrase-IN-1

DNA Gyrase Inhibitor

DNA Gyrase-IN-1 is a selective inhibitor of DNA gyrase, exhibiting a potent IC50 of 2.6 µM. This compound demonstrates significant antibacterial activity against Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 0.49 µM. DNA Gyrase-IN-1 is essential for research focused on developing therapeutics for tuberculosis and understanding gyrase-related mechanisms in bacterial replication.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3031486-11-7
Applications	DNA Gyrase Inhibitor
Formula	C₂₄H₂₄FN₇O₆
Molecular Weight	525.49
SMILES	C[C@@H]1N([C@@H](CN2C3=C(C4=C(C=C3CC5([C@]21[H])C(NC(NC5=O)=O)=O)C(OC[C@H]6NC(CC6)=O)=NO4)F)C)C#N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.