Fig. 1 · Structure
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DNA Gyrase-IN-13
DNA Gyrase Inhibitor
DNA Gyrase-IN-13 is a potent inhibitor of DNA gyrase, an essential enzyme for bacterial DNA replication and topology. This compound exhibits significant antibacterial activity, demonstrating an IC50 value of 1.81 μM against Staphylococcus aureus DNA gyrase. DNA Gyrase-IN-13 is valuable for research applications aimed at elucidating bacterial DNA manipulations and developing novel antibacterial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2247443-72-5 |
| Applications | DNA Gyrase Inhibitor |
| Formula | C15H21N3O3S |
| Molecular Weight | 323.41 |
| SMILES | CCCCCOC1=CC=C(C=C1)C(NNC(NC(C)=O)=S)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.