Fig. 1 · Structure
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DNA Gyrase-IN-16
DNA Gyrase Inhibitor
DNA Gyrase-IN-16 is a potent inhibitor of DNA gyrase, exhibiting an IC50 of 1.609 μM. This compound demonstrates significant antibacterial activity against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) of 3.125 μM for both strains. DNA Gyrase-IN-16 is a valuable tool for research focused on bacterial resistance mechanisms and the development of novel antibacterial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 756843-31-9 |
| Applications | DNA Gyrase Inhibitor |
| Formula | C17H15N3O3 |
| Molecular Weight | 309.32 |
| SMILES | O=C(C1=CC=C(N/N=C2C(NC3=C(C)C=C(C)C=C3\2)=O)C=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.