Dolcanatide

Name: Dolcanatide
Brand: Adooq Bioscience
SKU: A60864
Rating: 5 (288 reviews)

Catalog No.: A60864

GC-C Agonist

Dolcanatide is an orally active agonist of guanylate cyclase-C (GC-C). This compound exhibits laxative, anti-nociceptive, and anti-inflammatory properties, making it suitable for various experimental applications. Dolcanatide is particularly relevant in research focused on inflammatory bowel disease.

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Size	Price	Stock
1mg	$175.00	In stock
5mg	$450.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Dolcanatide is an orally active agonist of guanylate cyclase-C (GC-C). This compound exhibits laxative, anti-nociceptive, and anti-inflammatory properties, making it suitable for various experimental applications. Dolcanatide is particularly relevant in research focused on inflammatory bowel disease.

Product Information

Catalog Num	A60864
Formula	C65H104N18O26S4
Molecular Weight	1681.89
CAS Number	1092457-65-2
Sequence	{d-Asn}--Asp-Glu-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-{d-Leu} (Disulfide bridge: Cys4-Cys12; Cys7-Cys15)
Sequence shortening	{d-Asn}-DECELCVNVACTGC-{d-Leu} (Disulfide bridge: Cys4-Cys12; Cys7-Cys15)
SMILES	N(C([C@@H](NC([C@@H](NC([C@@H](CC(N)=O)N)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]2(C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@H](C)C)C(=O)N[C@@H](C)C(=O)N[C@@](CSSC1)(C(=O)N[C@@]([C@@H](C)O)(C(=O)NCC(=O)N[C@H](C(N[C@H](CC(C)C)C(O)=O)=O)CSSC2)[H])[H])[H]

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