Domatinostat tosylate

Catalog No.: A20986

HDAC1 inhibitor

Domatinostat tosylate

Domatinostat tosylate Chemical Structure

CAS NO. 1186222-89-8

Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).

Availability: In stock

Package Price Qty
5 mg
$108.00
10 mg
$186.00
50 mg
$552.00
100 mg
$1,104.00
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Biological Activity

Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.14 mL 80.68 mL 161.37 mL
0.5 mM 3.23 mL 16.14 mL 32.27 mL
1 mM 1.61 mL 8.07 mL 16.14 mL
5 mM 0.32 mL 1.61 mL 3.23 mL

*The above data is based on the productmolecular weight 619.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20986
Actions Inhibitor
M. Wt 619.71
Formula C30H29N5O6S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1186222-89-8
Synonyms 4SC-202, 4SC202, 4SC 202
SMILES O=C(NC1=CC=CC=C1N)/C=C/C2=CN(S(=O)(C3=CC=C(C4=CN(C)N=C4)C=C3)=O)C=C2.O=S(C5=CC=C(C)C=C5)(O)=O

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