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Form	MW
DOPG This page	775.04
DOPG sodium	797.03

DOPG

Phosphatidylglycerol Phospholipid

Dioleoylphosphatidylglycerol (DOPG) is a negatively charged phosphatidylglycerol phospholipid known for its significant presence in prokaryotic cell membranes and mitochondria. It exhibits a low phase transition temperature, allowing for the formation of stable vesicles. DOPG plays a crucial role in inhibiting inflammatory mediators in macrophages activated via heat shock protein B4 (HSPB4) and toll-like receptor 2 (TLR2). This reagent is essential for studies in membrane biology, drug-membrane interactions—particularly with negatively charged membranes—and the development of drug delivery systems, as well as investigations into sterile corneal inflammation and wound healing.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	62700-69-0
Applications	Phosphatidylglycerol Phospholipid
Formula	C₄₂H₇₉O₁₀P
Molecular Weight	775.04
Synonyms	Dioleoylphosphatidylglycerol
SMILES	OCC(O)COP(OC[C@@H](COC(CCCCCCC/C=C\CCCCCCCC)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.