Signaling Pathway
Product type
Important Notice: For research use only. We do not sell to patients.
Loading distributor info...
| Discription | Dorsomorphin, also known as BML-275, is a selective small molecule inhibitor of BMP signaling, which promotes cardiomyogenesis in embryonic stem cells. Dorsomorphin reverses the mesenchymal phenotype of breast cancer initiating cells by inhibition of bone morphogenetic protein signaling. | ||
|---|---|---|---|
| Targets |
|
| Catalog Num | A13720 |
|---|---|
| Formula | C24H27Cl2N5O |
| Molecular Weight | 472.41 |
| CAS Number | 1219168-18-9 |
| SMILES | C1CCN(CC1)CCOC2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC=C5)N=C3.Cl.Cl |
| Synonyms | Compound C, BML-275, BML275, BML 275 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | Insoluble | |
| Water | 87 mg/mL (184.15 mM) | ||
| Ethanol | Insoluble | ||
| In vivo | PBS | 14 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.17 mL | 105.84 mL | 211.68 mL |
| 0.5 mM | 4.23 mL | 21.17 mL | 42.34 mL |
| 1 mM | 2.12 mL | 10.58 mL | 21.17 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.23 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
