Dorzolamide HCL

Catalog No.: A10333

carbonic anhydrase inhibitor

Dorzolamide HCL Chemical Structure

CAS NO. 130693-82-2

Dorzolamide HCl is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide HCl is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $60.00

Special Price $48.00

50 mg

Regular Price: $100.00

Special Price $80.00

100 mg

Regular Price: $150.00

Special Price $120.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Dorzolamide HCl is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. Dorzolamide HCl is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.
Targets
Carbonic anhydrase II Carbonic anhydrase IV Carbonic anhydrase I
1.9 nM(Ki)31 nM(Ki)6000 nM(Ki)
In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.71 mL 138.54 mL 277.09 mL
0.5 mM 5.54 mL 27.71 mL 55.42 mL
1 mM 2.77 mL 13.85 mL 27.71 mL
5 mM 0.55 mL 2.77 mL 5.54 mL

*The above data is based on the productmolecular weight 360.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10333
Actions Inhibitor
M. Wt 360.9
Formula C10H17ClN2O4S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 130693-82-2
Synonyms Trusopt, Cosopt
SMILES CCN[[email protected]]1C[[email protected]@H](S(=O)(=O)C2=C1C=C(S2)S(=O)(=O)N)C.Cl

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