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DOTA-NHS-ester hexafluorophosphate TFA

BFC

DOTA-NHS-ester hexafluorophosphate TFA is a bifunctional chelator (BFC) that serves as a macrocyclic DOTA derivative designed for tumor pre-targeting applications. This reagent facilitates the efficient conjugation of peptides and radionuclides, making it valuable in cancer research and therapeutic studies. Its unique structure allows for optimized binding and functionalization, enhancing the efficacy of targeted treatments.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1823122-52-6
Applications	BFC
Formula	C₂₀H₃₁N₅O₁₀.C₂HF₃O₂.F₆P.H
Molecular Weight	761.48
SMILES	O=C(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(ON2C(CCC2=O)=O)=O)CC(O)=O)O.O=C(C(F)(F)F)O.[F-][P+5]([F-])([F-])([F-])([F-])[F-].[H+]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.