DPC 684 is a highly selective HIV-1 protease inhibitor that demonstrates potent inhibitory activity with an IC90 ranging from 5.7 to 40 nM and a Ki value of 0.021 nM. By competitively inhibiting HIV-1 protease, it effectively blocks the cleavage of viral polyproteins, thereby disrupting viral replication. DPC 684 exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant strains of HIV-1, making it a valuable tool for research in HIV biology and therapeutic development.
DPC 684 is a highly selective HIV-1 protease inhibitor that demonstrates potent inhibitory activity with an IC90 ranging from 5.7 to 40 nM and a Ki value of 0.021 nM. By competitively inhibiting HIV-1 protease, it effectively blocks the cleavage of viral polyproteins, thereby disrupting viral replication. DPC 684 exhibits low protein binding and offers broad-spectrum inhibition against various wild-type and mutant strains of HIV-1, making it a valuable tool for research in HIV biology and therapeutic development.
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