Fig. 1 · Structure
Documents & Downloads
DPM-1003
PTP1B Inhibitor
DPM-1003 is a potent PTP1B conformational inhibitor that specifically targets the non-catalytic disordered segment at the C-terminus of the PTP1B protein. This compound has demonstrated significant efficacy in reducing lung inflammation in murine models, highlighting its potential for therapeutic applications in inflammatory diseases. DPM-1003 serves as a valuable tool for researchers investigating the role of PTP1B in various biological processes and disease states.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3018836-86-4 |
| Applications | PTP1B Inhibitor |
| Formula | C35H57N3O3 |
| Molecular Weight | 567.85 |
| SMILES | O[C@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCC(OC)=O)C)([H])[C@@]4([C@@](CC(CC4)NCCCCNCC5=CN=CC=C5)([H])C1)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.