Fig. 1 · Structure
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DSPE-PEG-Biotin, MW 2000
PROTAC Linkers
DSPE-PEG-Biotin, MW 2000 is a polyethylene glycol (PEG) based linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of biotin to target proteins, enhancing their recognition and degradation by the cellular proteasome. Its application in PROTAC technology supports the development of novel therapeutics by enabling targeted protein modulation in cellular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 385437-57-0 |
| Applications | PROTAC Linkers |
| Molecular Weight | 2000(Average) |
| Synonyms | DSPE-PEG(2000) Biotin |
| SMILES | CCCCCCCCCCCCCCCCCC(O[C@](COP(OCCNC(COCCOCCNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O)=O)(O[Na])=O)([H])COC(CCCCCCCCCCCCCCCCC)=O)=O.[MW 2000].[n] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.