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Form	MW
DTS-201 sodium This page	1034.04
DTS-201	1012.06

DTS-201 sodium

Doxorubicin Prodrug

DTS-201 sodium is a peptidic prodrug of Doxorubicin designed to target solid tumors. Upon cleavage by endopeptidases in the tumor microenvironment, it releases metabolites that enter cancer cells and are converted into active Doxorubicin. This compound demonstrates significant antitumoral efficacy in preclinical models of prostate, breast, and lung cancers, making it a potential candidate for cancer therapy research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	372491-73-1
Applications	Doxorubicin Prodrug
Formula	C₄₉H₆₄N₅NaO₁₈
Molecular Weight	1034.04
SMILES	OC1=C2C(C(C3=C(OC)C=CC=C3C2=O)=O)=C(O)C([C@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC(CCNC(CCC([O-])=O)=O)=O)=O)=O)=O)=C1C[C@](O)(C4)C(CO)=O.[Na+]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.