Documents & Downloads

Other Forms

Form	MW
DTS-201 This page	1012.06
DTS-201 sodium	1034.04

DTS-201

Doxorubicin Prodrug

DTS-201 is a peptidic prodrug of Doxorubicin, designed to target tumor cells through selective cleavage by endopeptidases in the tumor microenvironment. Upon enzymatic activation, it generates active Doxorubicin metabolites that effectively enter the cell. This compound demonstrates significant antitumoral activity in prostate, breast, and lung cancer xenograft models, making it a valuable tool for research in cancer therapeutics.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	274912-87-7
Applications	Doxorubicin Prodrug
Formula	C₄₉H₆₅N₅O₁₈
Molecular Weight	1012.06
SMILES	OC(CCC(NCCC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@H]([C@H](O)[C@H](C)O1)C[C@]1([H])O[C@@H]2C3=C(C[C@](C(CO)=O)(O)C2)C(O)=C4C(C(C5=C(OC)C=CC=C5C4=O)=O)=C3O)=O)=O)=O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.