Dyrk1A-IN-11 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), exhibiting an EC50 of 0.0021 µM. This compound effectively inhibits the phosphorylation of Tau at threonine 212, with an EC50 value of 0.0361 µM. Dyrk1A-IN-11 is relevant for research into neurodegenerative diseases and the role of tau phosphorylation in cellular processes.
Dyrk1A-IN-11 is a potent inhibitor of dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), exhibiting an EC50 of 0.0021 µM. This compound effectively inhibits the phosphorylation of Tau at threonine 212, with an EC50 value of 0.0361 µM. Dyrk1A-IN-11 is relevant for research into neurodegenerative diseases and the role of tau phosphorylation in cellular processes.
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