E-5842 citrate is a selective σ receptor ligand with a Ki value of 4 nM for the σ1 receptor. This compound has been shown to enhance Fos protein levels in the medial prefrontal cortex and nucleus accumbens, while having no effect on protein levels in the striatum. E-5842 citrate is valuable for investigating the neurobiological mechanisms underlying psychiatric disorders.
E-5842 citrate is a selective σ receptor ligand with a Ki value of 4 nM for the σ1 receptor. This compound has been shown to enhance Fos protein levels in the medial prefrontal cortex and nucleus accumbens, while having no effect on protein levels in the striatum. E-5842 citrate is valuable for investigating the neurobiological mechanisms underlying psychiatric disorders.
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