Fig. 1 · Structure
Documents & Downloads
(E)-MS0019266
DNA Damage Repair Inhibitor
(E)-MS0019266 is a potent inhibitor of DNA damage repair that targets ribonucleotide reductase through the generation of reactive oxygen species. This compound downregulates the expression of genes associated with cell cycle arrest and mitosis, including polo-like kinase 1, kinesin family member 20a, cyclin B1, and aurora kinase A. (E)-MS0019266 serves as a valuable tool for research focused on elucidating the roles of ribonucleotide reductase and polo-like kinase 1 in cellular processes and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 21945-37-9 |
| Applications | DNA Damage Repair Inhibitor |
| Formula | C11H10N4 |
| Molecular Weight | 198.22 |
| SMILES | C1(/C=N/NC2=NC=CC=C2)=NC=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.