Fig. 1 · Structure
Documents & Downloads
(E)-tert-Butyldimethyl((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allyl)oxy)silane
PROTAC Linker
(E)-tert-Butyldimethyl((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allyl)oxy)silane serves as a versatile PROTAC linker, facilitating the development of targeted protein degradation strategies. This compound enables the effective conjugation of peptide ligands to E3 ligase recruiters, enhancing the selective degradation of target proteins. It is particularly useful in research applications focused on exploring and manipulating cellular pathways through targeted therapy.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 114653-19-9 |
| Applications | PROTAC Linker |
| Formula | C15H31BO3Si |
| Molecular Weight | 298.31 |
| SMILES | C(=C/CO[Si](C(C)(C)C)(C)C)\B1OC(C)(C)C(C)(C)O1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.