Fig. 1 · Structure
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(E/Z)-Icerguastat acetate
PPP1R15A Inhibitor
(E/Z)-Icerguastat acetate is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). This compound exhibits key biological activity by modulating the activity of protein phosphatases, which plays a critical role in the regulation of protein folding and cellular stress responses. Research applications include investigations into protein misfolding diseases, providing insights into the molecular mechanisms underlying these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 469866-31-7 |
| Applications | PPP1R15A Inhibitor |
| Formula | C10H13ClN4O2 |
| Molecular Weight | 256.69 |
| Synonyms | (E/Z)-Sephin1 acetate; (E/Z)-IFB-088 acetate |
| SMILES | O=C(C)O.ClC1=C(/C=N/NC(N)=N)C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.