Fig. 1 · Structure

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(E/Z)-NSC-687852

NSC-687852 Isomer

(E/Z)-NSC-687852 is an isomer of the compound NSC-687852, which serves as a specific inhibitor of the deubiquitinating enzymes UCHL5 and Usp14. This compound exhibits notable biological activity in the modulation of protein ubiquitination pathways, contributing to the regulation of cellular processes such as protein degradation and signaling. It is utilized in research applications aimed at understanding the roles of deubiquitinating enzymes in various disease contexts, including cancer and neurodegenerative disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 330450-45-8
Applications NSC-687852 Isomer
Formula C22H17N3O6
Molecular Weight 419.39
Synonyms (E/Z)-b-AP15
SMILES
O=C1/C(CN(C(C=C)=O)C/C1=C\C2=CC=C([N+]([O-])=O)C=C2)=C\C3=CC=C([N+]([O-])=O)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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