(E/Z)-PG-11047

Catalog No.: A73343
Endogenous Metabolite
(E/Z)-PG-11047 is a polyamine analog that targets polyamine metabolism and exhibits potential for lung cancer inhibition. This compound has been shown to effectively inhibit the growth of both non-small cell and small cell lung cancer cells. Through significant downregulation of polyamine synthetase activity, (E/Z)-PG-11047 induces alterations in polyamine levels, making it a valuable tool for research in lung cancer biology and therapeutic development.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(E/Z)-PG-11047 is a polyamine analog that targets polyamine metabolism and exhibits potential for lung cancer inhibition. This compound has been shown to effectively inhibit the growth of both non-small cell and small cell lung cancer cells. Through significant downregulation of polyamine synthetase activity, (E/Z)-PG-11047 induces alterations in polyamine levels, making it a valuable tool for research in lung cancer biology and therapeutic development.
Product Information
Catalog NumA73343
FormulaC14H32N4
Molecular Weight256.43
CAS Number949933-50-0
SMILESCCNCCCNC/C=C/CNCCCNCC
Synonyms(E/Z)-CGC-11047
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