Fig. 1 · Structure
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(E/Z)-VU0029767
mAChR Modulator
(E/Z)-VU0029767 is an allosteric modulator of M1 muscarinic acetylcholine receptors (mAChRs), enhancing receptor activity by increasing agonist affinity. This compound exhibits distinct properties across various experimental conditions, including its interaction with mutant M1 receptors and effects on downstream signaling pathways. (E/Z)-VU0029767 is employed in research to explore mAChR function and develop therapeutic strategies targeting related neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 326001-01-8 |
| Applications | mAChR Modulator |
| Formula | C21H21N3O3 |
| Molecular Weight | 363.41 |
| SMILES | O=C(N/N=C/C1=C2C=CC=CC2=CC=C1O)CNC3=CC=C(OCC)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.