EBL-3183

Name: EBL-3183
Brand: Adooq Bioscience
SKU: A48829
Rating: 5 (288 reviews)

Catalog No.: A48829

Metallo-β-Lactamase Inhibitor

EBL-3183 is a potent inhibitor of metallo-β-lactamases (MBLs) that targets the NDM-1 enzyme. This indole-2-carboxylate compound exhibits reversible, non-covalent, and competitive inhibition characterized by a pIC50 value of 7.7. EBL-3183 is valuable for research applications focused on combating antibiotic resistance and exploring mechanisms of MBL inhibition.

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EBL-3183 2872672-18-7 Metallo-β-Lactamase Inhibitor

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Biological Activity

Description	EBL-3183 is a potent inhibitor of metallo-β-lactamases (MBLs) that targets the NDM-1 enzyme. This indole-2-carboxylate compound exhibits reversible, non-covalent, and competitive inhibition characterized by a pIC50 value of 7.7. EBL-3183 is valuable for research applications focused on combating antibiotic resistance and exploring mechanisms of MBL inhibition.

Product Information

Catalog Num	A48829
Formula	C25H27FN4O6S
Molecular Weight	530.57
CAS Number	2872672-18-7
SMILES	C[C@H](N1C[C@]2(OC1=O)C[C@@H](C2)CN)C3=CC=CC4=C3NC(C(O)=O)=C4C5=CC=C(C(F)=C5)NS(C)(=O)=O

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