Fig. 1 · Structure

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Ebopiprant hydrochloride

PGF2α Receptor Antagonist

Ebopiprant hydrochloride is a selective antagonist of the prostaglandin F2α (PGF2α) receptor, exhibiting subnanomolar affinity with a Ki of 1 nM for the human receptor. This compound effectively inhibits PGF2α-mediated signaling pathways, making it valuable for research into conditions such as glaucoma, reproductive health, and inflammation. Its selective activity allows for the exploration of PGF2α's role in various physiological and pathological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2005486-32-6
Applications PGF2α Receptor Antagonist
Formula C30H35ClFN3O5S2
Molecular Weight 636.20
Synonyms OBE022 hydrochloride
SMILES
O=C(N[C@H](C1=CC=C(F)C=C1)CCOC([C@H](C(C)C)N)=O)[C@H](SCC2)N2S(C(C=C3)=CC=C3C4=CC=CC=C4)(=O)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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