Ebselen derivative 1 is a potent glutathione peroxidase (GPx) mimic with oral activity, designed to provide protective effects against oxidative damage. It exhibits significant protective capabilities against cisplatin-induced hair cell (HC) damage, effectively mitigating oxidative stress, apoptosis, and ferroptosis in hair cells. This compound serves as a valuable tool for research into cisplatin-induced hearing loss and related oxidative stress pathways.
Ebselen derivative 1 is a potent glutathione peroxidase (GPx) mimic with oral activity, designed to provide protective effects against oxidative damage. It exhibits significant protective capabilities against cisplatin-induced hair cell (HC) damage, effectively mitigating oxidative stress, apoptosis, and ferroptosis in hair cells. This compound serves as a valuable tool for research into cisplatin-induced hearing loss and related oxidative stress pathways.
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