Documents & Downloads

EC-0225

Folate Conjugate

EC-0225 is a folate conjugate designed to target folate receptor (FR)-positive cells. This compound combines a potent microtubule inhibitor with a DNA alkylating agent, effectively inhibiting the growth of FR-positive KB cells with an IC50 of approximately 1 nM. EC-0225 enables targeted delivery to advanced FR-positive tumors, minimizing systemic toxicity, making it a valuable tool for cancer research and therapeutic applications.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	926626-77-9
Applications	Folate Conjugate
Formula	C₁₀₃H₁₃₀N₂₀O₂₆S₄
Molecular Weight	2192.51
SMILES	O[C@@]1(CC)C[C@]2([H])C[C@@](C3=C(OC)C=C4C([C@@]5(CC6)[C@@]([C@](C(NNC(OCCSSC[C@H](C(O)=O)CC([C@@H](NC([C@H](NC([C@H](CC(O)=O)NC([C@H](CC)NC(CC[C@@H](C)NC(C7=CC=C(NCC8=CNC(C9=N8)=NC(N)=CC9=O)C=C7)=O)=O)=O)=O)CC(O)=O)=O)CNC(CCSSCCNC%10=C(C)C(C%11=C(C[C@@]%12(OC)N%11C[C@H]%13[C@@H]%12N%13)C%10=O)=O)=O)=O)=O)=O)(O)[C@H](O)[C@@]%14(CC)[C@]5([H])N6CC=C%14)([H])N4C)=C3)(C(OC)=O)C%15=C(CC[N@@](C2)C1)C%16=CC=CC=C%16N%15

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.