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Biological Activity
Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively.
| In vitro | DMSO | 65 mg/mL (186.57 mM) | |
| Water | Insoluble | ||
| Ethanol | 65 mg/mL (186.57 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.7 mL | 143.52 mL | 287.03 mL |
| 0.5 mM | 5.74 mL | 28.7 mL | 57.41 mL |
| 1 mM | 2.87 mL | 14.35 mL | 28.7 mL |
| 5 mM | 0.57 mL | 2.87 mL | 5.74 mL |
*The above data is based on the productmolecular weight 348.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14067 |
|---|---|
| CAS No. | 164650-44-6 |
| Formula | C18H22F2N4O |
| M. Wt | 348.39 |
| Purity | >98% |
| Synonyms | KP-103, KP103, KP 103 |
| SMILES | C[[email protected]@H](N1CCC(CC1)=C)[[email protected]@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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