Fig. 1 · Structure
Documents & Downloads
EGR-1-IN-3
EGR-1-DNA Binding Disruptor
EGR-1-IN-3 is a potent disruptor of early growth response 1 (EGR-1) DNA binding. This compound effectively inhibits TNFα-induced EGR-1 binding to DNA, leading to a reduction in the expression of pro-inflammatory genes such as TSLP, IL-31, IL-6, and CCL2. EGR-1-IN-3 is valuable for research applications focused on inflammatory diseases and mechanisms of transcriptional regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1700655-93-1 |
| Applications | EGR-1-DNA Binding Disruptor |
| Formula | C31H31N3O6S |
| Molecular Weight | 573.66 |
| SMILES | S=C(N1N=C(C2=CC=C3C=CC=CC3=C2O)CC1C4=C(OC)C=C(OC)C=C4OC)NC5=CC=C(OC)C=C5OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.