Fig. 1 · Structure
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EIDD-2749
RdRp Inhibitor
EIDD-2749, also known as 4'-Fluorouridine, is an orally active inhibitor of RNA-dependent RNA polymerase (RdRp). This compound effectively obstructs the replication of respiratory syncytial virus (RSV) and SARS-CoV-2, while also demonstrating activity against hepatitis C virus (HCV) and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 represents a promising therapeutic candidate for the treatment of COVID-19 and serves as a valuable tool for research involving other RNA viruses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1613589-24-4 |
| Applications | RdRp Inhibitor |
| Formula | C9H11FN2O6 |
| Molecular Weight | 262.19 |
| Synonyms | 4'-FlU; 4'-Fluorouridine |
| SMILES | O=C1NC(N([C@@H]2O[C@@](CO)(F)[C@@H](O)[C@H]2O)C=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.