EIPA (L593754; MH 12-43) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA (L593754; MH 12-43) also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
EIPA (L593754; MH 12-43) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA (L593754; MH 12-43) also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
Targets
Target
Value
Product Information
Catalog Num
A20092
Formula
C11H18ClN7O
Molecular Weight
299.76
CAS Number
1154-25-2
SMILES
O=C(C1=NC(Cl)=C(N(CC)C(C)C)N=C1N)NC(N)=N
Synonyms
L593754, L 593754, L-593754; MH 12-43, MH-12-43, MH12-43
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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