Catalog No.: A12686


Eltrombopag Chemical Structure

CAS NO. 496775-61-2

Eltrombopag is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

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10 mg
50 mg
100 mg
10mM * 1mL in DMSO
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Biological Activity

Eltrombopag is an agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.
thrombopoietin receptor (TpoR)
In vitro DMSO Warmed: 22 mg/mL (49.72 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.6 mL 113 mL 226 mL
0.5 mM 4.52 mL 22.6 mL 45.2 mL
1 mM 2.26 mL 11.3 mL 22.6 mL
5 mM 0.45 mL 2.26 mL 4.52 mL

*The above data is based on the productmolecular weight 442.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12686
CAS No. 496775-61-2
Formula C25H22N4O4
M. Wt 442.47
Purity >98%
Synonyms SB 497115, SB497115, SB-497115
SMILES CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N/N=C/3\C=CC=C(C3=O)C4=CC(=CC=C4)C(=O)O)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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