Fig. 1 · Structure
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Emlenoflast
NLRP3 Inhibitor
Emlenoflast (MCC7840) is a potent and selective inhibitor of the NLRP3 inflammasome, exhibiting an IC50 of less than 100 nM. This sulfonylurea compound plays a critical role in modulating inflammatory responses and is valuable for research into various inflammatory diseases. Its ability to inhibit the NLRP3 pathway makes it a significant tool for investigating mechanisms of inflammation and developing therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1995067-59-8 |
| Applications | NLRP3 Inhibitor |
| Formula | C19H24N4O3S |
| Molecular Weight | 388.48 |
| Synonyms | MCC7840 |
| SMILES | O=S(C1=NN(C(C)C)C=C1)(NC(NC2=C3CCCC3=CC4=C2CCC4)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.