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endo-BCN-PEG4-Val-Cit-PAB-MMAE

Catalog No.: A41352
Drug-Linker Conjugates for ADC
endo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable linker specifically designed for antibody-drug conjugates (ADCs), facilitating the targeted delivery of therapeutic agents. This compound features a 4-unit polyethylene glycol (PEG) chain and incorporates a BCN group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its versatility is highly applicable in the development of ADCs, enhancing the efficacy and specificity of cancer therapies.
endo-BCN-PEG4-Val-Cit-PAB-MMAE 2762519-08-2 Drug-Linker Conjugates for ADC
Grouped product items
Size Price Stock Qty
1mg
$335.00
In stock
5mg
$780.00
In stock
10mg
$1,260.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionendo-BCN-PEG4-Val-Cit-PAB-MMAE is a cleavable linker specifically designed for antibody-drug conjugates (ADCs), facilitating the targeted delivery of therapeutic agents. This compound features a 4-unit polyethylene glycol (PEG) chain and incorporates a BCN group that enables efficient strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Its versatility is highly applicable in the development of ADCs, enhancing the efficacy and specificity of cancer therapies.
Product Information
Catalog NumA41352
FormulaC80H127N11O19
Molecular Weight1546.93
CAS Number2762519-08-2
SMILESCC[C@@H]([C@H](N(C([C@@H](NC([C@@H](N(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCOCCOCCOCCNC(OC[C@@H]2[C@@]3([H])[C@]2([H])CCC#CCC3)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1)=O)C)C(C)C)=O)C(C)C)=O)C)[C@H](OC)CC(N4CCC[C@H]4[C@H](OC)[C@H](C(N[C@@H]([C@@H](O)C5=CC=CC=C5)C)=O)C)=O)C
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC
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