Fig. 1 · Structure
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Endothall
PP2A Inhibitor
Endothall is a selective inhibitor of protein phosphatase 2A (PP2A), exhibiting an IC50 of 90 nM for PP2A and 5 µM for PP1. This compound demonstrates significant potential in cancer chemotherapy by modulating cellular signaling pathways. Additionally, Endothall serves as a useful herbicide, enhancing its applicability in agricultural research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 145-73-3 |
| Applications | PP2A Inhibitor |
| Formula | C8H10O5 |
| Molecular Weight | 186.16 |
| Synonyms | Endothal |
| SMILES | OC(C1C(C2CCC1O2)C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.